Life Science Buffers
Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.
Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.
Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.
The choice of buffer for a particular biological reaction or site depends on several factors:
- Temperature
- Desired or target pH
- Buffer toxicity (to the system)
- Buffer interactions with other system components
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Filtered Search Results
| Packaging | Plastic bottle |
|---|---|
| Physical Form | Liquid |
| Recommended Storage | Ambient temperatures |
| CAS | 1135-40-6 |
|---|---|
| Molecular Weight (g/mol) | 221.32 |
| MDL Number | MFCD00003837 |
| Physical Form | Liquid |
| pH | 9.0 |
| SMILES | OS(=O)(=O)CCCNC1CCCCC1 |
| Recommended Storage | Ambient temperatures |
| Concentration | 0.5 M |
| IUPAC Name | 3-(cyclohexylamino)propane-1-sulfonic acid |
| InChI Key | PJWWRFATQTVXHA-UHFFFAOYSA-N |
| Molecular Formula | C9H19NO3S |
| Molecular Weight (g/mol) | 89.14 |
|---|---|
| Color | Colorless |
| Physical Form | Liquid |
| SMILES | CC(C)(N)CO |
| Concentration | 0.2 M |
| InChI Key | CBTVGIZVANVGBH-UHFFFAOYSA-N |
| CAS | 4958-39-8 |
| MDL Number | MFCD00008051 |
| pH | 9.5 |
| Synonym | 2-Amino-2-methyl-1-propanol |
| Recommended Storage | Keep cold |
| IUPAC Name | 2-amino-2-methylpropan-1-ol |
| Molecular Formula | C4H11NO |
| Odor | Odorless |
Thermo Scientific Chemicals Phosphate-buffered saline (PBS, 10X), with Triton∣r X-100
Ideal for maintaining a constant pH.
| Physical Form | Liquid |
|---|---|
| Chemical Name or Material | Phosphate Buffered Saline (PBS) |
| Recommended Storage | Ambient temperatures |
| Concentration | 10 X |
MOPSO sodium salt
CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.24 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYNA-M IUPAC Name: sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
| CAS | 79803-73-9 |
|---|---|
| Molecular Weight (g/mol) | 247.24 |
| SMILES | [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O |
| IUPAC Name | sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate |
| InChI Key | WSFQLUVWDKCYSW-UHFFFAOYNA-M |
| Molecular Formula | C7H14NNaO5S |
Thermo Scientific Chemicals TAPS, 99+%, for biochemistry
CAS: 29915-38-6 Molecular Formula: C7H17NO6S Molecular Weight (g/mol): 243.27 MDL Number: MFCD00007538 InChI Key: YNLCVAQJIKOXER-UHFFFAOYSA-N Synonym: 3-[Tris(hydroxymethyl)methylamino]-1-propanesulfonic acid PubChem CID: 121591 IUPAC Name: 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid SMILES: OCC(CO)(CO)NCCCS(O)(=O)=O
| PubChem CID | 121591 |
|---|---|
| CAS | 29915-38-6 |
| Molecular Weight (g/mol) | 243.27 |
| MDL Number | MFCD00007538 |
| SMILES | OCC(CO)(CO)NCCCS(O)(=O)=O |
| Synonym | 3-[Tris(hydroxymethyl)methylamino]-1-propanesulfonic acid |
| IUPAC Name | 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid |
| InChI Key | YNLCVAQJIKOXER-UHFFFAOYSA-N |
| Molecular Formula | C7H17NO6S |
TRIS, 0.5 M Buffer Solution, pH 6.8, PROMO, Thermo Scientific Chemicals
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.14 g/mol MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O
| PubChem CID | 6503 |
|---|---|
| CAS | 77-86-1 |
| Molecular Weight (g/mol) | 121.14 g/mol |
| ChEBI | CHEBI:9754 |
| MDL Number | MFCD00004679 |
| SMILES | C(C(CO)(CO)N)O |
| IUPAC Name | 2-amino-2-(hydroxymethyl)propane-1,3-diol |
| InChI Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| Molecular Formula | C4H11NO3 |
| MDL Number | MFCD00236358 |
|---|---|
| Synonym | Tris-Borate-EDTA buffer |
Tris, MP Biomedicals™
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol, Tromethamine, Tris-[hydroxymethyl]amino-methane PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O
| PubChem CID | 6503 |
|---|---|
| CAS | 77-86-1 |
| Molecular Weight (g/mol) | 121.136 |
| ChEBI | CHEBI:9754 |
| SMILES | C(C(CO)(CO)N)O |
| Synonym | 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol, Tromethamine, Tris-[hydroxymethyl]amino-methane |
| IUPAC Name | 2-amino-2-(hydroxymethyl)propane-1,3-diol |
| InChI Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| Molecular Formula | C4H11NO3 |
TRIS, MP Biomedicals™
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.14 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: Tris-[hydroxymethyl]aminomethane,THAM, 2-Amino-2-(hydroxymethyl)- 1,3-propandiol,Tromethamine,Trometamol
| CAS | 77-86-1 |
|---|---|
| Molecular Weight (g/mol) | 121.14 |
| MDL Number | MFCD00004679 |
| Synonym | Tris-[hydroxymethyl]aminomethane,THAM, 2-Amino-2-(hydroxymethyl)- 1,3-propandiol,Tromethamine,Trometamol |
| InChI Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| Molecular Formula | C4H11NO3 |
Hanks' Balanced Salts, Without Sodium Bicarbonate, MP Biomedicals™
Hanks' Balanced Salts, Without Sodium Bicarbonate, Orange Powder
| Color | Orange |
|---|---|
| Physical Form | Powder |
| pH | 6.0 to 7.0 (before adjustment with sodium bicarbonate) |
TrisHydroxymethyl)Aminomethane ACS AR, Macron Fine Chemicals™
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O
| PubChem CID | 6503 |
|---|---|
| CAS | 77-86-1 |
| Molecular Weight (g/mol) | 121.136 |
| ChEBI | CHEBI:9754 |
| SMILES | C(C(CO)(CO)N)O |
| IUPAC Name | 2-amino-2-(hydroxymethyl)propane-1,3-diol |
| InChI Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| Molecular Formula | C4H11NO3 |
Novus Biologicals™ PBS Tablets
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Phosphate buffered saline tablets pH 7.4
PIPES, Monosodium Salt, Biological Buffer, High Purity, 98.5%, Spectrum™ Chemical
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
CAS: 10010-67-0 Molecular Formula: C8H17N2NaO6S2 Molecular Weight (g/mol): 324.34 MDL Number: MFCD00065472 InChI Key: OGGAIRCLBMGXCZ-UHFFFAOYSA-M IUPAC Name: sodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethane-1-sulfonate SMILES: [Na+].OS(=O)(=O)CCN1CCN(CCS([O-])(=O)=O)CC1
| CAS | 10010-67-0 |
|---|---|
| Molecular Weight (g/mol) | 324.34 |
| MDL Number | MFCD00065472 |
| SMILES | [Na+].OS(=O)(=O)CCN1CCN(CCS([O-])(=O)=O)CC1 |
| IUPAC Name | sodium 2-[4-(2-sulfoethyl)piperazin-1-yl]ethane-1-sulfonate |
| InChI Key | OGGAIRCLBMGXCZ-UHFFFAOYSA-M |
| Molecular Formula | C8H17N2NaO6S2 |